• 江南·体育(JN SPORTS)官方网站,江南体育app下载

    |
    |
    EN
    • 业务咨询

      中国:

      Email: marketing@hangzhouaijunshengwu.com

      业务咨询专线:400-780-8018

      (仅限服务咨询,其他事宜请拨打川沙总部电话)

      川沙总部电话: +86 (21) 5859-1500

      海外:

      +1(626)986-9880(U.S. - West Coast)

      0044 7790 816 954 (Europe)

      Email:marketing@medicilon.com

    在线留言×
    点击切换
    Customer Center
    客户中心

    研究人员报告了一种具有细胞渗透性的选择性METTL3纳摩尔抑制剂UZH1a,作者感谢美迪西合成了UZH1a和UZH1b

    2023-07-05
    |
    访问量:

    54.png

    The methylase METTL3 is the writer enzyme of the N6‐methyladenosine (m6A) modification of RNA.

    Here researchers report a nanomolar inhibitor of METTL3 (UZH1a) which is selective and cell‐permeable, while its enantiomer UZH1b is essentially inactive. 

    The authors thank Medicilon for the synthesis of the UZH1a and UZH1b compounds.

    Reference:

    Elena V Moroz-Omori, et al. METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes. ChemMedChem. 2021 Oct 6;16(19):3035-3043. doi: 10.1002/cmdc.202100291. 

    相关新闻
    江南·体育(JN SPORTS)官方网站